Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb3tm1Nwg mutation
(0 available);
any
Efnb3 mutation
(11 available)
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nervous system
N |
• normal hippocampal architecture
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• reduced early LTP but no significant defects of basal synaptic transmission parameters or NMDA receptor component
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb3tm1Nwg mutation
(0 available);
any
Efnb3 mutation
(11 available)
|
|
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behavior/neurological
nervous system
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• corticospinal tract nerve fibers aberrantly cross the spinal cord midline to the contralateral side
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• corticospinal tract nerve fibers aberrantly cross the spinal cord midline to the contralateral side
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• lumbar segments of the spinal cords of neonates exhibit synchronous left-right ventral root activity instead of the left-right alternating activity observed in wild-type after NMDA and serotonin application
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb3tm1Nwg mutation
(0 available);
any
Efnb3 mutation
(11 available)
|
|
|
behavior/neurological
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• mirrored limb movement resulting in a hopping locomotion
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nervous system
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• axons aberrantly crossed the midline boundary of the spinal cord
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