Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Iqgap1tm1Aber mutation
(1 available);
any
Iqgap1 mutation
(102 available)
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digestive/alimentary system
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• older mice exhibit hyperplasia and dysplasia of the mucosal layer of the stomach
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• mucosal dysplasia observed in older mice
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liver/biliary system
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• incidence is decreased compared to Iqgap1tm1Vs single homozygotes but is increased compared to controls
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mortality/aging
N |
• unlike Iqgap1tm1Vs single homozygotes, survival durations are not significantly different from controls
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neoplasm
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• incidence is decreased compared to Iqgap1tm1Vs single homozygotes but is increased compared to controls
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• when present hepatocellular carcinomas are smaller than those in Iqgap1tm1Vs single homozygotes
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homeostasis/metabolism