All Phenotypes Omp<tm1Flm> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Omp^tm1Flm
targeted mutation 1, Frank L Margolis
MGI:2387862

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Omp^tm1Flm/Omp^tm1Flm	involves: 129S1/Sv	MGI:3622787

Allelic Composition	Omp^tm1Flm/Omp^tm1Flm
Genetic Background	involves: 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Omp^tm1Flm mutation (1 available); any Omp mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

taste/olfaction

abnormal olfactory system physiology ( J:36149 )

• electoolfactogram response magnitudes from olfactory epithelium of null mice in response to isoamyl acetate are 25% lower than in wild-type; responses to all other chemical odors tested are 20-40% smaller than in wild-type

homeostasis/metabolism

abnormal enzyme/coenzyme activity ( J:36149 )

• tyrosine hydroxylase activity in null olfactory bulbs are 65% lower than wild-type

nervous system

small olfactory bulb ( J:36149 )

• olfactory bulb weight is 15% less in mutants than in wild-type at 1 to 2 months after birth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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