All Phenotypes Vav1<tm1Bbd> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vav1^tm1Bbd
targeted mutation 1, Mariano Barbacid
MGI:2387839

Summary

2 genotypes

Allelic Composition	Vav1^tm1Bbd/Vav1^tm1Bbd
Genetic Background	involves: 129S2/SvPas * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vav1^tm1Bbd mutation (0 available); any Vav1 mutation (63 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• lethality between E3.5 and E7.5

embryo

• cultured embryos fail to hatch from the zona pellucida

Allelic Composition	Vav1^tm1Bbd/Vav1⁺
Genetic Background	involves: 129S2/SvPas * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vav1^tm1Bbd mutation (0 available); any Vav1 mutation (63 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:22517 )

• slight distortion in favor of heterozygous mice over wild type mice at birth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24