Phenotypes associated with this allele

• Allele Symbol: Adrb3^tm1Jpg
• Allele Name: targeted mutation 1, Jean-Paul Giacobino
• Allele ID: MGI:2387777
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adrb3^tm1Jpg/Adrb3^tm1Jpg	involves: 129S4/SvJae * C57BL/6J	MGI:2387778

Genotype
MGI:2387778

hm1

• Allelic Composition: Adrb3^tm1Jpg/Adrb3^tm1Jpg
• Genetic Background: involves: 129S4/SvJae * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:42702 )

• when fed conventional or high-fat diet

increased percent body fat/body weight ( J:42702 )

• when fed conventional or high-fat diet

behavior/neurological

polyphagia ( J:42702 )

• when fed high-fat diet from age 6 to 11 weeks

growth/size/body

increased susceptibility to weight gain ( J:42702 )

• when fed high-fat diet, compared to gain of control animals

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:42702 )

N • circulating leptin concentrations same as control mice for both conventional and high-fat diet