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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr320tm1.1Mkg
targeted mutation 1.1, Mark Groudine
MGI:2386946
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr320tm1.1Mkg/Rr320tm1.1Mkg involves: 129 MGI:3810423
ht2
 		Rr320tm1.1Mkg/Rr320+ involves: 129 MGI:3810422


Genotype
MGI:3810423
hm1
Allelic
Composition		 Rr320tm1.1Mkg/Rr320tm1.1Mkg
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:3810422
ht2
Allelic
Composition		 Rr320tm1.1Mkg/Rr320+
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased survivor rate ( J:60714 )
• only 50% of mice survive to adulthood

embryo
pale yolk sac ( J:60714 )
• is observed in E15.5 embryos

growth/size/body
decreased body size ( J:60714 )
• mice are smaller than controls

hematopoietic system
anemia ( J:60714 )
• is observed in E15.5 embryos and newborns

liver/biliary system
pale liver ( J:60714 )
• is observed in E15.5 embryos

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
beta thalassemia DOID:12241 OMIM:613985
 J:60714




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory