Phenotypes associated with this allele

• Allele Symbol: Fmn1^tm1Led
• Allele Name: targeted mutation 1, Philip Leder
• Allele ID: MGI:2386598
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fmn1^tm1Led/Fmn1^tm1Led	involves: 129S6/SvEvTac * Black Swiss	MGI:3796841
ht2	Fmn1^tm1Led/Fmn1^tm2Led	involves: 129S6/SvEvTac * Black Swiss	MGI:3796843
ht3	Fmn1^ld-TgBri137/Fmn1^tm1Led	involves: 129S6/SvEvTac * Black Swiss * C57BL/6 * SJL	MGI:3796844

Genotype
MGI:3796841

hm1

• Allelic Composition: Fmn1^tm1Led/Fmn1^tm1Led
• Genetic Background: involves: 129S6/SvEvTac * Black Swiss

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

absent kidney ( J:50647 )

• at P1, twelve of 151 mice (7.94%) exhibit bilateral renal agenesis

single kidney ( J:50647 )

• at P1, nine of 151 mice (5.96%) exhibit unilateral renal agenesis

limbs/digits/tail

limbs/digits/tail phenotype ( J:50647 )

N • limbs develop normally

Genotype
MGI:3796843

ht2

• Allelic Composition: Fmn1^tm1Led/Fmn1^tm2Led
• Genetic Background: involves: 129S6/SvEvTac * Black Swiss

renal/urinary system

renal/urinary system phenotype ( J:50647 )

N • no renal agenesis is observed

Genotype
MGI:3796844

ht3

• Allelic Composition: Fmn1^ld-TgBri137/Fmn1^tm1Led
• Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6 * SJL

renal/urinary system

absent kidney ( J:50647 )

• at P1, four of 50 mice (8%) exhibit bilateral renal agenesis

single kidney ( J:50647 )

• at P1, two of 50 compound heterozygotes (4%) exhibit unilateral renal agenesis