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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(RP23-291P1)1Flp
transgene insertion 1, Figge, Lammert and Paigen
MGI:2386569
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(RP23-291P1)1Flp/? involves: 129S1/SvImJ * FVB/NJ MGI:3626083


Genotype
MGI:3626083
tg1
Allelic
Composition		 Tg(RP23-291P1)1Flp/?
Genetic
Background		 involves: 129S1/SvImJ * FVB/NJ
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No mouse lines available in IMSR.
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
abnormal bile composition ( J:104062 )
• increased bile hydrophobicity
• development of cholesterol crystals by day 4 of lithogenic diet
gallstones ( J:104062 )
• accelerated gallstone formation on a lithogenic diet
• 25% incidence of gallsones by day 4 of lithogenic diet; 80% incidence by day 7

endocrine/exocrine glands
abnormal bile composition ( J:104062 )
• increased bile hydrophobicity
• development of cholesterol crystals by day 4 of lithogenic diet




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory