Phenotypes associated with this allele

• Allele Symbol: Igf1r^tm1Mhz
• Allele Name: targeted mutation 1, Martin Holzenberger
• Allele ID: MGI:2386327
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Igf1r^tm1Mhz/Igf1r^tm1Mhz	involves: 129/Sv * C57BL/6	MGI:3775299

Genotype
MGI:3775299

hm1

• Allelic Composition: Igf1r^tm1Mhz/Igf1r^tm1Mhz
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:63460 )

• between 4 and 6 weeks of age, mice weight less than wild-type and heterozygous mice

postnatal growth retardation ( J:63460 )

• between 4 and 6 weeks of age, mice weight less than wild-type and heterozygous mice

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:63460 )

N • mice exhibit normal circulating insulin growth factor levels