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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hrastm1Esn
targeted mutation 1, Eugenio Santos
MGI:2385945
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hrastm1Esn/Hrastm1Esn involves: 129X1/SvJ * C57BL/6N MGI:3036351
cx2
 		Hrastm1Esn/Hrastm1Esn
Nrastm1Rak/Nrastm1Rak 		involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6N MGI:3036364


Genotype
MGI:3036351
hm1
Allelic
Composition		 Hrastm1Esn/Hrastm1Esn
Genetic
Background		 involves: 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Esn mutation (1 available); any Hras mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:67374 )
• viable and fertile; no gross morphological or histological abnormalities, defects in neuronal development or defects in lymphocyte cell populations were detected in homozygous mice




Genotype
MGI:3036364
cx2
Allelic
Composition		 Hrastm1Esn/Hrastm1Esn
Nrastm1Rak/Nrastm1Rak
Genetic
Background		 involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Esn mutation (1 available); any Hras mutation (29 available)
Nrastm1Rak mutation (0 available); any Nras mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:67374 )
• mice grew normally, were fertile and did not exhibit any obvious phenotype; however, fewer than the expected number of adult compound homozygous mice were obtained in crosses




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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory