Phenotypes associated with this allele

• Allele Symbol: Adipoq^tm1Tka
• Allele Name: targeted mutation 1, Takashi Kadowaki
• Allele ID: MGI:2384094
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adipoq^tm1Tka/Adipoq^tm1Tka	involves: 129S4/SvJae * C57BL/6	MGI:2387162
ht2	Adipoq^tm1Tka/Adipoq^+	involves: 129S4/SvJae * C57BL/6	MGI:2387163

Genotype
MGI:2387162

hm1

• Allelic Composition: Adipoq^tm1Tka/Adipoq^tm1Tka
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal vascular wound healing ( J:77876 )

• increase in neointimal thickening after mechanical injury to femoral artery

homeostasis/metabolism

abnormal vascular wound healing ( J:77876 )

• increase in neointimal thickening after mechanical injury to femoral artery

increased circulating triglyceride level ( J:77876 )

impaired glucose tolerance ( J:77876 )

• after glucose tolerance tests vs. wild-type littermates

insulin resistance ( J:77876 )

• in insulin tolerance tests

Genotype
MGI:2387163

ht2

• Allelic Composition: Adipoq^tm1Tka/Adipoq⁺
• Genetic Background: involves: 129S4/SvJae * C57BL/6

homeostasis/metabolism

impaired glucose tolerance ( J:77876 )

• after 10 weeks on high-fat diet, blood glucose concentrations before and after oral glucose tolerance tests were higher than littermate controls

insulin resistance ( J:77876 )

• in insulin tolerance tests