Phenotypes associated with this allele

• Allele Symbol: Myoc^tm1Rjo
• Allele Name: targeted mutation 1, Randy L Johnson
• Allele ID: MGI:2183810
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myoc^tm1Rjo/Myoc^tm1Rjo	either: 129S7/SvEvBrd or (involves: 129S7/SvEvBrd * C57BL/6)	MGI:3055595

Genotype
MGI:3055595

hm1

• Allelic Composition: Myoc^tm1Rjo/Myoc^tm1Rjo
• Genetic Background: either: 129S7/SvEvBrd or (involves: 129S7/SvEvBrd * C57BL/6)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:72628 )

• at 3-16 months, homozygotes retaining the floxed neomycin cassette are viable, fertile and show no significant differences in intraocular pressure or clinical signs of glaucoma relative to wild-type

• histological analysis of the iridocorneal angle, retina, and optic nerve revealed no ocular anomalies in homozygous mutant mice

• at 3-12 months, homozygotes display no ultrastructural defects in the trabecular meshwork, cornea, or iris