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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tgfbr2tm1.1Karl
targeted mutation 1.1, Stefan Karlsson
MGI:2183504
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tgfbr2tm1.1Karl/Tgfbr2tm1.1Karl involves: 129/Sv * C57BL/6 MGI:2669277


Genotype
MGI:2669277
hm1
Allelic
Composition		 Tgfbr2tm1.1Karl/Tgfbr2tm1.1Karl
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tgfbr2tm1.1Karl mutation (0 available); any Tgfbr2 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
enlarged pericardium ( J:77844 )
• E9.5 - E10.5

embryo

growth/size/body
decreased embryo size ( J:77844 )

hematopoietic system
abnormal erythropoiesis ( J:77844 )
• absence of erythropoiesis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory