Phenotypes associated with this allele

• Allele Symbol: Pspn^tm1Bjh
• Allele Name: targeted mutation 1, Brian J Hoffer
• Allele ID: MGI:2183393
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pspn^tm1Bjh/Pspn^tm1Bjh	involves: 129S1/Sv * 129X1/SvJ	MGI:3487226

Genotype
MGI:3487226

hm1

• Allelic Composition: Pspn^tm1Bjh/Pspn^tm1Bjh
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

increased susceptibility to ischemic brain injury ( J:77733 )

• recovery from stroke caused by middle cerebral artery occlusion was diminished between day 2 and day 30 after the stroke, as measured by vertical activity

increased cerebral infarct size ( J:77733 )

• infarct volume 4X normal

homeostasis/metabolism

increased susceptibility to ischemic brain injury ( J:77733 )

• recovery from stroke caused by middle cerebral artery occlusion was diminished between day 2 and day 30 after the stroke, as measured by vertical activity

increased cerebral infarct size ( J:77733 )

• infarct volume 4X normal