About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Per1tm1Saco
targeted mutation 1, Paolo Sassone-Corsi
MGI:2182634
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Per1tm1Saco/Per1tm1Saco B6.129S2-Per1tm1Saco MGI:3845776
hm2
 		Per1tm1Saco/Per1tm1Saco involves: 129S2/SvPas MGI:3845777
hm3
 		Per1tm1Saco/Per1tm1Saco involves: 129S2/SvPas * C57BL/6 MGI:3845775
ht4
 		Per1tm1Saco/Per1+ involves: 129S2/SvPas MGI:3845778


Genotype
MGI:3845776
hm1
Allelic
Composition		 Per1tm1Saco/Per1tm1Saco
Genetic
Background		 B6.129S2-Per1tm1Saco
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Per1tm1Saco mutation (0 available); any Per1 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:70850 )
• under constant dark conditions




Genotype
MGI:3845777
hm2
Allelic
Composition		 Per1tm1Saco/Per1tm1Saco
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Per1tm1Saco mutation (0 available); any Per1 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal circadian behavior phase ( J:98340 )
• following exposure to prolonged light the magnitude of the induced phase delay is significantly larger compared to heterozygous and wild-type controls
abnormal circardian behavior entrainment ( J:98340 )
• impaired entrainment to long day periods under dim light conditions
• mice fail to entrain to long day periods under skeleton light conditions (L/D/L/D, 0.5/16/0.5/7)




Genotype
MGI:3845775
hm3
Allelic
Composition		 Per1tm1Saco/Per1tm1Saco
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Per1tm1Saco mutation (0 available); any Per1 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:70850 )
• under constant dark conditions




Genotype
MGI:3845778
ht4
Allelic
Composition		 Per1tm1Saco/Per1+
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Per1tm1Saco mutation (0 available); any Per1 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal circadian behavior phase ( J:98340 )
• following exposure to prolonged light the magnitude of the induced phase delay is slightly but significantly larger compared to wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory