Phenotypes associated with this allele

• Allele Symbol: skimp
• Allele Name: skijumper
• Allele ID: MGI:2182130
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	skimp/skimp	involves: C3H/HeH	MGI:2182134

Genotype
MGI:2182134

hm1

• Allelic Composition: skimp/skimp
• Genetic Background: involves: C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Electron micrograph of liver

mortality/aging

postnatal lethality, complete penetrance ( J:77535 )

• death occurs within a few days of birth

homeostasis/metabolism

decreased circulating glucose level ( J:77535 )

• mice were described as having has low levels of glucose

decreased circulating ketone body level ( J:77535 )

• mice were described as having has low levels of ketones

decreased glycogen level ( J:77535 )

• mice were described as having has low blood levels of glycogen

muscle

opisthotonus ( J:77535 )

• mice were described as opisthotonic, with characteristic arching upward of the head; the front limbs are often held parallel to the body and then stretched upwards, with the paws being higher off the ground than the spine

behavior/neurological

opisthotonus ( J:77535 )

• mice were described as opisthotonic, with characteristic arching upward of the head; the front limbs are often held parallel to the body and then stretched upwards, with the paws being higher off the ground than the spine

liver/biliary system

abnormal liver morphology ( J:77535 )

• livers exhibit about 80% fewer lipid droplets that are also smaller in size than in controls