All Phenotypes Csn2<tm1Psim> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Csn2^tm1Psim
targeted mutation 1, Paul Simons
MGI:2182074

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Csn2^tm1Psim/Csn2^tm1Psim	involves: 129P2/OlaHsd * MF1	MGI:3696685

Allelic Composition	Csn2^tm1Psim/Csn2^tm1Psim
Genetic Background	involves: 129P2/OlaHsd * MF1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csn2^tm1Psim mutation (0 available); any Csn2 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal milk composition ( J:18947 )

• less milk protein in milk from homozygous mothers

• casein micelles are smaller than normal and totally lack beta-casein

integument

abnormal milk composition ( J:18947 )

• less milk protein in milk from homozygous mothers

• casein micelles are smaller than normal and totally lack beta-casein

cellular

maternal effect ( J:18947 )

• growth rate of pups nursed by homozygous mothers is significantly slower than normal as a result of deficiencies in milk composition

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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