Phenotypes associated with this allele

• Allele Symbol: Gba1^tm2Rlp
• Allele Name: targeted mutation 2, Richard L Proia
• Allele ID: MGI:2180204
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gba1^tm2Rlp/Gba1^tm2Rlp	involves: 129S4/SvJae	MGI:2651551

Genotype
MGI:2651551

hm1

• Allelic Composition: Gba1^tm2Rlp/Gba1^tm2Rlp
• Genetic Background: involves: 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Phenotypes of Gba1^tm1Rlp/Gba1^tm1Rlp and Gba1^tm2Rlp/Gba1^tm2Rlp mice after birth

mortality/aging

postnatal lethality, complete penetrance ( J:46243 )

• animals died at 24-48 hours after birth

behavior/neurological

absent gastric milk in neonates ( J:46243 )

• neonates did not appear to feed, absence of milk in stomach

growth/size/body

decreased birth body size ( J:46243 )

• small size at birth

homeostasis/metabolism

dehydration ( J:46243 )

integument

hyperkeratosis ( J:46243 )

reddish skin ( J:46243 )

wrinkled skin ( J:46243 )

decreased skin turgor ( J:46243 )