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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prphtm1Jpj
targeted mutation 1, Jean-Pierre Julien
MGI:2180052
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prphtm1Jpj/Prphtm1Jpj involves: C57BL/6 MGI:3042863


Genotype
MGI:3042863
hm1
Allelic
Composition		 Prphtm1Jpj/Prphtm1Jpj
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prphtm1Jpj mutation (0 available); any Prph mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:76218 )
N
• overall axonal structure was normal
• overall, number and caliber of large myelinated axons from spinal motor neurons was normal
• retinal ganglion cells morphologically similar to control mice
abnormal axon morphology ( J:76218 )
• reduced numbers of unmyelinated sensory axons
abnormal sensory neuron morphology ( J:76218 )
• reduced numbers of unmyelinated sensory axons




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory