All Phenotypes Ckm<tm2Bew> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ckm^tm2Bew
targeted mutation 2, Be Wieringa
MGI:2179994

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ckm^tm2Bew/Ckm^tm2Bew	involves: 129S7/SvEvBrd * C57BL/6	MGI:3849164
ht2	Ckm^tm1Bew/Ckm^tm2Bew	involves: 129S7/SvEvBrd * C57BL/6	MGI:3849168

Allelic Composition	Ckm^tm2Bew/Ckm^tm2Bew
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ckm^tm2Bew mutation (0 available); any Ckm mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:20440 )

N	• both anaerobic and aerobic energy potentials are normal

muscle

impaired skeletal muscle contractility ( J:20440 )

• a 4% drop in force generated by gastrocnemius-plantaris-soleus muscle complex within the first eight twitches using 5 Hz stimulation

Allelic Composition	Ckm^tm1Bew/Ckm^tm2Bew
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ckm^tm1Bew mutation (0 available); any Ckm mutation (34 available)
Ckm^tm2Bew mutation (0 available); any Ckm mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

impaired skeletal muscle contractility ( J:20440 )

• a 9% drop in force generated by gastrocnemius-plantaris-soleus muscle complex within the first eight twitches using 5 Hz stimulation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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