Phenotypes associated with this allele

• Allele Symbol: Styx^tm1Jedi
• Allele Name: targeted mutation 1, Jack E Dixon
• Allele ID: MGI:2179177
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Styx^tm1Jedi/Styx^tm1Jedi	either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: C57BL/6)	MGI:2661881

Genotype
MGI:2661881

hm1

• Allelic Composition: Styx^tm1Jedi/Styx^tm1Jedi
• Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: C57BL/6)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

asthenozoospermia ( J:74767 )

♂ • residual sperm was either immotile or exhibited uncoordinated mobility

abnormal spermatogenesis ( J:74767 )

♂ • greater than a 1000-fold decrease in spermatozoa-like cells

teratozoospermia ( J:74767 )

♂ • tail defects were observed in less than 50% of the immotile sperm

globozoospermia ( J:74767 )

♂ • observed spermatozoa-like cells exhibited either round heads, blunted acrosomes with misattached flagellum, gaps in detached acrosomes, or pinhead morphology

abnormal spermatid morphology ( J:74767 )

♂ • impaired spermatid differentiation

♂ • loss of spermatids due to premature shedding into the lumen and increased cellular death

male infertility ( J:74767 )

♂

cellular

teratozoospermia ( J:74767 )

♂ • tail defects were observed in less than 50% of the immotile sperm

globozoospermia ( J:74767 )

♂ • observed spermatozoa-like cells exhibited either round heads, blunted acrosomes with misattached flagellum, gaps in detached acrosomes, or pinhead morphology

abnormal spermatid morphology ( J:74767 )

♂ • impaired spermatid differentiation

♂ • loss of spermatids due to premature shedding into the lumen and increased cellular death

asthenozoospermia ( J:74767 )

♂ • residual sperm was either immotile or exhibited uncoordinated mobility