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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pou3f4del-J
deletion, Jackson
MGI:2179137
Summary 6 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pou3f4del-J/Pou3f4del-J C3HeB/FeJ-Pou3f4del-J/J MGI:2656641
ht2
 		Pou3f4del-J/Pou3f4+ C3HeB/FeJ-Pou3f4del-J/J MGI:3698745
cx3
 		Marveld2tm1.1Sria/Marveld2tm1.1Sria
Pou3f4del-J/Y 		involves: 129X1/SvJ * C3Heb/FeJ * C57BL/6J MGI:5550098
cx4
 		Marveld2tm1.1Sria/Marveld2tm1.1Sria
Pou3f4del-J/Pou3f4del-J 		involves: 129X1/SvJ * C3Heb/FeJ * C57BL/6J MGI:5550099
cx5
 		Cldn9nmf329/Cldn9nmf329
Pou3f4del-J/Y 		involves: C3HeB/FeJ * C57BL/6J MGI:4357858
ot6
 		Pou3f4del-J/Y C3HeB/FeJ-Pou3f4del-J/J MGI:2656640


Genotype
MGI:2656641
hm1
Allelic
Composition		 Pou3f4del-J/Pou3f4del-J
Genetic
Background		 C3HeB/FeJ-Pou3f4del-J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pou3f4del-J mutation (1 available); any Pou3f4 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
head bobbing ( J:83049 , J:116914 )
(J:83049)
(J:116914)

hearing/vestibular/ear
impaired hearing ( J:83049 )
• hearing is impaired
absent linear vestibular evoked potential ( J:116914 )
• VESPs are absent at the maximum stimulus intensity used




Genotype
MGI:3698745
ht2
Allelic
Composition		 Pou3f4del-J/Pou3f4+
Genetic
Background		 C3HeB/FeJ-Pou3f4del-J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pou3f4del-J mutation (1 available); any Pou3f4 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
absent linear vestibular evoked potential ( J:116914 )
• in one of two mice tested, VESPs are absent at the maximum stimulus intensity used




Genotype
MGI:5550098
cx3
Allelic
Composition		 Marveld2tm1.1Sria/Marveld2tm1.1Sria
Pou3f4del-J/Y
Genetic
Background		 involves: 129X1/SvJ * C3Heb/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Marveld2tm1.1Sria mutation (0 available); any Marveld2 mutation (29 available)
Pou3f4del-J mutation (1 available); any Pou3f4 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:201580 )
N
• unlike in mutant mice wild-type for Pou3f4, no outer hair cell degeneration is seen at P16




Genotype
MGI:5550099
cx4
Allelic
Composition		 Marveld2tm1.1Sria/Marveld2tm1.1Sria
Pou3f4del-J/Pou3f4del-J
Genetic
Background		 involves: 129X1/SvJ * C3Heb/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Marveld2tm1.1Sria mutation (0 available); any Marveld2 mutation (29 available)
Pou3f4del-J mutation (1 available); any Pou3f4 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:201580 )
N
• unlike in mutant mice wild-type for Pou3f4, no outer hair cell degeneration is seen at P16




Genotype
MGI:4357858
cx5
Allelic
Composition		 Cldn9nmf329/Cldn9nmf329
Pou3f4del-J/Y
Genetic
Background		 involves: C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cldn9nmf329 mutation (1 available); any Cldn9 mutation (9 available)
Pou3f4del-J mutation (1 available); any Pou3f4 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:152154 )
N
• mice do not exhibit loss of outer hair cells unlike in Cldn9nmf329 homozygotes




Genotype
MGI:2656640
ot6
Allelic
Composition		 Pou3f4del-J/Y
Genetic
Background		 C3HeB/FeJ-Pou3f4del-J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pou3f4del-J mutation (1 available); any Pou3f4 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
head bobbing ( J:83049 , J:116914 )
(J:83049)
(J:116914)

hearing/vestibular/ear
impaired hearing ( J:83049 )
• hearing is impaired
absent linear vestibular evoked potential ( J:116914 )
• VESPs are absent at the maximum stimulus intensity used




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory