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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Chrna6tm1Nchx
targeted mutation 1, Nicolas Champtiaux
MGI:2179133
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Chrna6tm1Nchx/Chrna6tm1Nchx involves: 129S2/SvPas * CD-1 MGI:2663154


Genotype
MGI:2663154
hm1
Allelic
Composition		 Chrna6tm1Nchx/Chrna6tm1Nchx
Genetic
Background		 involves: 129S2/SvPas * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chrna6tm1Nchx mutation (0 available); any Chrna6 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal brain morphology ( J:74587 )
• decrease in number of high affinity binding sites for nicotinic ligands, 3H-nicotine, 3H-epibaditine, and 3H-cytisin, in the terminal region of the retinal ganglion and complete disappearance of high-affinity [125]alpha-conotoxinMII binding sites




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory