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Allele Symbol Allele Name Allele ID |
Brca2tm2Arge targeted mutation 2, Argiris Efstratiadis MGI:2177211 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mammary tumors occur after long latency of at least 13 months of age
• T50 for tumor-free survival is approximately 17 months of age
• at the end of the 20 month observation period, 20 of 26 animals developed mammary tumors; control animals developed none
• tumor pathology corresponded to two characteristic types, solid carcinoma and adenoacanthoma, with a mixture of the two types frequently appearing in the same tumor mass
|
|
• mammary tumors occur after long latency of at least 13 months of age
• T50 for tumor-free survival is approximately 17 months of age
• at the end of the 20 month observation period, 20 of 26 animals developed mammary tumors; control animals developed none
• tumor pathology corresponded to two characteristic types, solid carcinoma and adenoacanthoma, with a mixture of the two types frequently appearing in the same tumor mass
|
|
• mammary tumors occur after long latency of at least 13 months of age
• T50 for tumor-free survival is approximately 17 months of age
• at the end of the 20 month observation period, 20 of 26 animals developed mammary tumors; control animals developed none
• tumor pathology corresponded to two characteristic types, solid carcinoma and adenoacanthoma, with a mixture of the two types frequently appearing in the same tumor mass
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| breast cancer | DOID:1612 |
OMIM:114480 |
J:70564 | |
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mammary tumors occur after long latency of at least 13 months of age
• T50 for tumor-free survival is approximately 17 months of age
• at the end of the 20 month observation period, 20 of 26 animals developed mammary tumors; control animals developed none
• tumor pathology corresponded to two characteristic types, solid carcinoma and adenoacanthoma, with a mixture of the two types frequently appearing in the same tumor mass
|
|
• mammary tumors occur after long latency of at least 13 months of age
• T50 for tumor-free survival is approximately 17 months of age
• at the end of the 20 month observation period, 20 of 26 animals developed mammary tumors; control animals developed none
• tumor pathology corresponded to two characteristic types, solid carcinoma and adenoacanthoma, with a mixture of the two types frequently appearing in the same tumor mass
|
|
• mammary tumors occur after long latency of at least 13 months of age
• T50 for tumor-free survival is approximately 17 months of age
• at the end of the 20 month observation period, 20 of 26 animals developed mammary tumors; control animals developed none
• tumor pathology corresponded to two characteristic types, solid carcinoma and adenoacanthoma, with a mixture of the two types frequently appearing in the same tumor mass
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| breast cancer | DOID:1612 |
OMIM:114480 |
J:70564 | |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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