Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Neurog2tm3(Ascl1)Fgu mutation
(1 available);
any
Neurog2 mutation
(18 available)
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nervous system
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• in E11.5 embryos decrease in the number of dI2 neurons
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• in E11.5 embryos the number of dI3 neurons is elevated
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• in E11.5 embryos the number of dI5 neurons is elevated
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Neurog2tm3(Ascl1)Fgu mutation
(1 available);
any
Neurog2 mutation
(18 available)
|
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nervous system
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• in E11.5 embryos, increase in dI3 numbers
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• in E11.5 embryos, increase in dI5 numbers
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Allelic
Composition |
Neurog2tm3(Ascl1)Fgu/Neurog2+
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Genetic
Background |
involves: 129S1/Sv * 129X1/SvJ * CD-1 |
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Neurog2tm3(Ascl1)Fgu mutation
(1 available);
any
Neurog2 mutation
(18 available)
|
|
|
nervous system
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• there is a reduced number of ectopic ventral-type neurons with a lateral rather than dorsal location compared to Neurog2 nulls
• at E12.5, there is an increase in the number of cells expressing a panneuronal marker compared to wild-type
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nervous system
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• no differentiation of DRG neurons is seen in double mutants
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Analysis Tools