All Phenotypes Srf<tm1Nor> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Srf^tm1Nor
targeted mutation 1, Alfred Nordheim
MGI:2158696

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Srf^tm1Nor/Srf^tm1Nor	involves: 129P2/OlaHsd	MGI:3608114

Allelic Composition	Srf^tm1Nor/Srf^tm1Nor
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srf^tm1Nor mutation (0 available); any Srf mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• no embryos detected after E12.5

embryo

abnormal gastrulation ( J:50876 )

• display aberrant folding of ectoderm and endoderm at E7.5 and E8.5

embryonic growth retardation ( J:50876 )

• at E7.5, exhibit delayed development and display late egg cylinder stage morphology

decreased embryo size ( J:50876 )

• embryos are smaller at E7.5 but appear normal at E6.5

absent mesoderm ( J:50876 )

growth/size/body

embryonic growth retardation ( J:50876 )

• at E7.5, exhibit delayed development and display late egg cylinder stage morphology

decreased embryo size ( J:50876 )

• embryos are smaller at E7.5 but appear normal at E6.5

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