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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Otx2tm5(OTX2)Asim
targeted mutation 5, Antonio Simeone
MGI:2157780
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Otx2tm5(OTX2)Asim/Otx2tm5(OTX2)Asim involves: 129P2/OlaHsd * C57BL/6 * DBA/2 MGI:3796055


Genotype
MGI:3796055
hm1
Allelic
Composition
Otx2tm5(OTX2)Asim/Otx2tm5(OTX2)Asim
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otx2tm5(OTX2)Asim mutation (0 available); any Otx2 mutation (50 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• forebrain patterning is similar to that observed in Otx2tm3(otd)Asim homozygotes based on marker expression
• forebrain patterning is similar to that observed in Otx2tm3(otd)Asim homozygotes based on marker expression

growth/size/body
• a low percentage (4.7%) exhibit a 'headless' phenotype, while the remainder show mild, moderate, or severe phenotypes at 10.5 days post coitum (dpc)
• a low percentage (4.7%) exhibit a 'headless' phenotype





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory