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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apobtm5Sgy
targeted mutation 5, Stephen G Young
MGI:2157108
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Apobtm5Sgy/Apobtm5Sgy involves: 129S4/SvJae * C57BL/6 MGI:2662538


Genotype
MGI:2662538
hm1
Allelic
Composition		 Apobtm5Sgy/Apobtm5Sgy
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apobtm5Sgy mutation (0 available); any Apob mutation (224 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality ( J:51549 )
• 50% do not survive until weaning

homeostasis/metabolism
decreased circulating LDL cholesterol level ( J:51549 )
• on high fat diet, low plasma LDL is observed
decreased circulating VLDL cholesterol level ( J:51549 )
• on high fat diet, low plasma VLDL is observed; VLDL particles are small




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory