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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lyntm1Mhi
targeted mutation 1, Margaret Hibbs
MGI:2157016
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lyntm1Mhi/Lyntm1Mhi involves: 129S1/Sv MGI:3767996


Genotype
MGI:3767996
hm1
Allelic
Composition		 Lyntm1Mhi/Lyntm1Mhi
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyntm1Mhi mutation (4 available); any Lyn mutation (67 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased neutrophil cell number ( J:72269 )
• in the spleen and peripheral blood
decreased spleen weight ( J:72269 )
• unlike Lyn null mice, mice do not develop age-dependent splenomegaly and spleen weight are modestly lower than in wild-type mice

immune system
increased neutrophil cell number ( J:72269 )
• in the spleen and peripheral blood
decreased spleen weight ( J:72269 )
• unlike Lyn null mice, mice do not develop age-dependent splenomegaly and spleen weight are modestly lower than in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory