All Phenotypes Pax6<7Neu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pax6^7Neu
7, Neuherberg
MGI:2156738

Summary

2 genotypes

Allelic Composition	Pax6^7Neu/Pax6^7Neu
Genetic Background	involves: 102 * C3H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax6^7Neu mutation (1 available); any Pax6 mutation (93 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal craniofacial morphology ( J:73625 )

• severe craniofacial defects

vision/eye

anophthalmia ( J:73625 )

Allelic Composition	Pax6^7Neu/Pax6⁺
Genetic Background	involves: 102 * C3H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax6^7Neu mutation (1 available); any Pax6 mutation (93 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal iris morphology ( J:73625 )

• dysplasia

irregularly shaped pupil ( J:73625 )

• triangular shape

anterior iris synechia ( J:63651 , J:73625 )

cataract ( J:73625 )

anterior polar cataract ( J:63651 )

• anterior polar opacity

microphthalmia ( J:63651 , J:73625 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Peters anomaly		DOID:0060673	OMIM:604229	J:73625

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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