All Phenotypes Amh<tm2Bhr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Amh^tm2Bhr
targeted mutation 2, Richard R Behringer
MGI:2156547

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Amh^tm2Bhr/Amh^tm2Bhr	involves: 129S7/SvEvBrd * C57BL/6	MGI:3042246
ht2	Amh^tm2Bhr/Amh^tm2.1Bhr	involves: 129S7/SvEvBrd * C57BL/6	MGI:3042248

Allelic Composition	Amh^tm2Bhr/Amh^tm2Bhr
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amh^tm2Bhr mutation (0 available); any Amh mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

male pseudohermaphroditism ( J:58474 )

• male mice developed both testes and Mullerian duct derivatives, including uteri and oviducts

secondary sex reversal ( J:58474 )

Allelic Composition	Amh^tm2Bhr/Amh^tm2.1Bhr
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amh^tm2.1Bhr mutation (0 available); any Amh mutation (24 available)
Amh^tm2Bhr mutation (0 available); any Amh mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal secondary sex determination ( J:58474 )

• Mullerian duct-derived tissues are only partially regressed in male mice

• in spite of partially retained uterine tissue, male mice were fertile

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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