Phenotypes associated with this allele

• Allele Symbol: Lbw2^NZW/LacScr
• Allele Name: NZW/LacScr
• Allele ID: MGI:2155969
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lbw2^NZW/LacScr/Lbw2^NZW/LacScr	involves: NZB * NZW	MGI:3580624
ht2	Lbw2^NZB/BlScr/Lbw2^NZW/LacScr	involves: NZB * NZW	MGI:2175442

Genotype
MGI:3580624

hm1

• Allelic Composition: Lbw2^NZW/LacScr/Lbw2^NZW/LacScr
• Genetic Background: involves: NZB * NZW

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:98150 )

N • decreased mortality

homeostasis/metabolism

edema ( J:98150 )

• decreased edema

increased urine protein level ( J:98150 )

• decreased proteinuria

renal/urinary system

increased urine protein level ( J:98150 )

• decreased proteinuria

immune system

decreased IgG level ( J:98150 )

• decreased IgG deposits in the glomeruli

decreased IgM level ( J:98150 )

• decreased IgM deposits in the glomeruli

decreased autoantibody level ( J:98150 )

• decreased IgM anti-ssDNA autoantibody production

hematopoietic system

decreased IgG level ( J:98150 )

• decreased IgG deposits in the glomeruli

decreased IgM level ( J:98150 )

• decreased IgM deposits in the glomeruli

Genotype
MGI:2175442

ht2

• Allelic Composition: Lbw2^NZB/BlScr/Lbw2^NZW/LacScr
• Genetic Background: involves: NZB * NZW

mortality/aging

premature death ( J:98150 , J:20991 )

• accelerated mortality (J:98150)

• early mortality (J:20991)

immune system

increased autoantibody level ( J:98150 )

• increased autoantibody production

increased anti-chromatin antibody level ( J:98150 )

glomerulonephritis ( J:20991 )

renal/urinary system

glomerulonephritis ( J:20991 )