All Phenotypes Cdx1<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cdx1⁺
wild type
MGI:2154546

Summary

6 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Cdx1^tm1Pgr/Cdx1⁺	involves: 129 * C57BL/6	MGI:3817890
ht2	Cdx1^tm1Lhn/Cdx1⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3817887
ht3	Cdx1^tm2Lhn/Cdx1⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	MGI:3837955
ht4	Cdx1^tm3Lhn/Cdx1⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	MGI:3837957
cx5	Cdx1^tm1Lhn/Cdx1⁺ Rarg^tm1Ipc/Rarg^tm1Ipc	involves: 129 * C57BL/6	MGI:3817900
cx6	Cdx1^tm1Pgr/Cdx1⁺ Rarg^tm1Ipc/Rarg^tm1Ipc	involves: 129 * C57BL/6	MGI:3817898

Allelic Composition	Cdx1^tm1Pgr/Cdx1⁺
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx1^tm1Pgr mutation (1 available); any Cdx1 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

cervical vertebral transformation ( J:86514 )

• 56% of mice exhibit possible transformation of the C2 vertebrae with slightly narrower C1 neural arches and/or a short cartilaginous ectopic anterior arch of the atlas on C2

fusion of vertebral arches ( J:86514 )

• 26% of mice have neural arch fusions of V1 to V4

Allelic Composition	Cdx1^tm1Lhn/Cdx1⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx1^tm1Lhn mutation (0 available); any Cdx1 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal basioccipital bone morphology ( J:86514 )

• a small posterior extension of the basioccipital bone occurs in 12% of mice

cervical vertebral transformation ( J:86514 )

• 12 % of mice exhibit possible transformation of the C2 vertebrae with slightly narrower C1 neural arches and/or a short cartilaginous ectopic anterior arch of the atlas on C2

craniofacial

abnormal basioccipital bone morphology ( J:86514 )

• a small posterior extension of the basioccipital bone occurs in 12% of mice

Allelic Composition	Cdx1^tm2Lhn/Cdx1⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx1^tm2Lhn mutation (0 available); any Cdx1 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal cervical atlas morphology ( J:146408 )

• 13% of mice exhibit an anterior arch of the atlas that is fused to V2

cervical vertebral transformation ( J:146408 )

• 40% of mice exhibit a C2 to C1 transformation

abnormal vertebral arch morphology ( J:146408 )

• 13% of mice exhibit a malformed C2 neural arch

Allelic Composition	Cdx1^tm3Lhn/Cdx1⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx1^tm3Lhn mutation (0 available); any Cdx1 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal cervical atlas morphology ( J:146408 )

• 42% of mice exhibit an anterior arch of the atlas that is fused to V2

cervical vertebral transformation ( J:146408 )

• 42% of mice exhibit an anterior arch of the atlas that is fused to V2

abnormal vertebral arch morphology ( J:146408 )

• 12% of mice exhibit a malformed C2 neural arch

• 6% of mice exhibit a neural arch fusion of vertebrae 1 and 2

Allelic Composition	Cdx1^tm1Lhn/Cdx1⁺ Rarg^tm1Ipc/Rarg^tm1Ipc
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx1^tm1Lhn mutation (0 available); any Cdx1 mutation (14 available)
Rarg^tm1Ipc mutation (2 available); any Rarg mutation (150 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

cervical vertebral transformation ( J:86514 )

• 33% of mice exhibit possible transformation of the C2 vertebrae with slightly narrower C1 neural arches and/or a short cartilaginous ectopic anterior arch of the atlas on C2

abnormal vertebral arch morphology ( J:86514 )

• 11% of mice have thick neural arches in the vertebrae

fusion of vertebral arches ( J:86514 )

• 11% of mice have neural arch fusions of V1 to V4

Allelic Composition	Cdx1^tm1Pgr/Cdx1⁺ Rarg^tm1Ipc/Rarg^tm1Ipc
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx1^tm1Pgr mutation (1 available); any Cdx1 mutation (14 available)
Rarg^tm1Ipc mutation (2 available); any Rarg mutation (150 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

cervical vertebral transformation ( J:86514 )

• 90% of mice exhibit possible transformation of the C2 vertebrae with slightly narrower C1 neural arches and/or a short cartilaginous ectopic anterior arch of the atlas on C2

abnormal vertebral arch morphology ( J:86514 )

• 60% of mice have thick neural arches in the vertebrae

abnormal vertebral spinous process morphology ( J:86514 )

• 30% of mice have posterior spinous processes on V10 and sometimes V9

fusion of vertebral arches ( J:86514 )

• 40% of mice have neural arch fusions of V1 to V4

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