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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lore1SS
SS
MGI:2154179
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lore1SS/Lore1SS involves: LS * SS MGI:3042200
hm2
 		Lore1SS/Lore1SS LS.SS-Lore1 MGI:3528287
ht3
 		Lore1LS/Lore1SS involves: LS * SS MGI:3042207


Genotype
MGI:3042200
hm1
Allelic
Composition		 Lore1SS/Lore1SS
Genetic
Background		 involves: LS * SS
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lore1SS mutation (0 available); any Lore1 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
improved righting response ( J:76104 )
• decreased righting response time following alcohol challenge

homeostasis/metabolism
abnormal blood homeostasis ( J:76104 )
• increased blood alcohol level following alcohol challenge




Genotype
MGI:3528287
hm2
Allelic
Composition		 Lore1SS/Lore1SS
Genetic
Background		 LS.SS-Lore1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lore1SS mutation (0 available); any Lore1 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal nervous system physiology ( J:93175 )
• animals exhibit enhanced GabaA receptor-mediated inhibitory postsynaptic currents when administered 80 mM ethanol




Genotype
MGI:3042207
ht3
Allelic
Composition		 Lore1LS/Lore1SS
Genetic
Background		 involves: LS * SS
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lore1LS mutation (0 available); any Lore1 mutation (2 available)
Lore1SS mutation (0 available); any Lore1 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired righting response ( J:76104 )
• increased loss of righting response (LORR) following alcohol challenge




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory