All Phenotypes Lore1<SS> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lore1^SS
SS
MGI:2154179

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lore1^SS/Lore1^SS	involves: LS * SS	MGI:3042200
hm2	Lore1^SS/Lore1^SS	LS.SS-Lore1	MGI:3528287
ht3	Lore1^LS/Lore1^SS	involves: LS * SS	MGI:3042207

Allelic Composition	Lore1^SS/Lore1^SS
Genetic Background	involves: LS * SS

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lore1^SS mutation (0 available); any Lore1 mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

improved righting response ( J:76104 )

• decreased righting response time following alcohol challenge

homeostasis/metabolism

abnormal blood homeostasis ( J:76104 )

• increased blood alcohol level following alcohol challenge

Allelic Composition	Lore1^SS/Lore1^SS
Genetic Background	LS.SS-Lore1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lore1^SS mutation (0 available); any Lore1 mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal nervous system physiology ( J:93175 )

• animals exhibit enhanced GabaA receptor-mediated inhibitory postsynaptic currents when administered 80 mM ethanol

Allelic Composition	Lore1^LS/Lore1^SS
Genetic Background	involves: LS * SS

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lore1^LS mutation (0 available); any Lore1 mutation (2 available)
Lore1^SS mutation (0 available); any Lore1 mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired righting response ( J:76104 )

• increased loss of righting response (LORR) following alcohol challenge

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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