All Phenotypes Bmp5<se-5RD300H> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Bmp5^se-5RD300H
short ear deletion 5RD300H, Oak Ridge
MGI:2153907

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bmp5^se-5RD300H/Bmp5^se-5RD300H	involves: 101/Rl * C3H/Rl	MGI:4822376
ht2	Bmp5^se/Bmp5^se-5RD300H	involves: 101/Rl * C3H/Rl	MGI:4822377

Allelic Composition	Bmp5^se-5RD300H/Bmp5^se-5RD300H
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp5^se-5RD300H mutation (1 available); any Bmp5 mutation (116 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between somite formation and embryo turning, complete penetrance ( J:5268 )

• homozygous mutant mice die prior to day 8

prenatal lethality, complete penetrance ( J:12013 , J:100221 )

embryo

decreased embryo size ( J:5268 )

• reduced size relative to normal

absent mesoderm ( J:5268 )

• nearly total absence of mesoderm

increased trophoblast giant cell number ( J:5268 )

abnormal extraembryonic ectoderm morphology ( J:5268 )

• extensive proliferation of extraembryonic ectoderm

growth/size/body

decreased embryo size ( J:5268 )

• reduced size relative to normal

Allelic Composition	Bmp5^se/Bmp5^se-5RD300H
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp5^se mutation (72 available); any Bmp5 mutation (116 available)
Bmp5^se-5RD300H mutation (1 available); any Bmp5 mutation (116 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

small ears ( J:100221 )

hearing/vestibular/ear

small ears ( J:100221 )

growth/size/body

small ears ( J:100221 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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