All Phenotypes Rxra<tm4.1Ipc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rxra^tm4.1Ipc
targeted mutation 4.1, Pierre Chambon
MGI:2153829

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rxra^tm4.1Ipc/Rxra^tm4.1Ipc	involves: 129S2/SvPas	MGI:4358396
ht2	Rxra^tm2Ipc/Rxra^tm4.1Ipc	involves: 129	MGI:4358395

Allelic Composition	Rxra^tm4.1Ipc/Rxra^tm4.1Ipc
Genetic Background	involves: 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rxra^tm4.1Ipc mutation (0 available); any Rxra mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:67149 )

• fetuses die between E12.5 and E16.5

vision/eye

abnormal eye development ( J:67149 )

• all E13.5 embryos exhibit ocular defects

cardiovascular system

abnormal vasculogenesis ( J:67149 )

• E13.5 embryos have poor vascular irrigation

homeostasis/metabolism

edema ( J:67149 )

• all E13.5 embryos are oedemic

integument

pallor ( J:67149 )

• all E13.5 embryos are pale

Allelic Composition	Rxra^tm2Ipc/Rxra^tm4.1Ipc
Genetic Background	involves: 129