All Phenotypes Lim2<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lim2⁺
wild type
MGI:2153124

Summary

2 genotypes

Allelic Composition	Lim2^Aca47/Lim2⁺
Genetic Background	C57BL/6J-Lim2^Aca47

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lim2^Aca47 mutation (1 available); any Lim2 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:179533 )

N	• at 4 months, mice exhibit normal visual abilities

abnormal lens morphology ( J:179533 )

• lenses exhibit reduced thickness compared with wild-type mice

• lenses are less affected in size and stability compared with homozygous mice

• however, lenses remain transparent

small lens ( J:179533 )

• at 20 weeks of age, not as severe as in homozygous mice

abnormal eye size ( J:179533 )

• reduced axial eye length

Allelic Composition	Lim2^To3/Lim2⁺
Genetic Background	involves: 102 * C3H/He * T STOCK

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lim2^To3 mutation (2 available); any Lim2 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

total cataract ( J:34877 )

• total opacity

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 19 multiple types		DOID:0110263	OMIM:615277	J:46338

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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