Analysis Tools
endocrine/exocrine glands
nervous system
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• at E16.5, cerebellar primordium is reduced compared to in wild-type mice
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Allele Symbol Allele Name Allele ID |
Ptf1atm1Pkwe targeted mutation 1, Peter K Wellauer MGI:2152066 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E16.5, cerebellar primordium is reduced compared to in wild-type mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• though alive 1 day before birth, fewer than expect mice survive the 2 to 3 hours after birth before nursing
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• at E16, mice have fewer glucagon producing cells than in wild-type mice
• however, the number of glucagon producing cells at E12 is normal
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• mice lack a pancreas
• however, all endocrine islet cell types are detected after birth in the mesentery that normally harbors the pancreas until E16
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• at birth
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• unlike in wild-type mice, glucagon producing cells and pancreatic endocrine cells are located in the spleen at birth
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• at birth
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• unlike in wild-type mice, glucagon producing cells and pancreatic endocrine cells are located in the spleen at birth
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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