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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hoxc13tm3Mrc
targeted mutation 3, Mario R Capecchi
MGI:2151694
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hoxc13tm3Mrc/Hoxc13tm3Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:3832427
ht2
 		Hoxc13tm3Mrc/Hoxc13+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:3832428


Genotype
MGI:3832427
hm1
Allelic
Composition		 Hoxc13tm3Mrc/Hoxc13tm3Mrc
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxc13tm3Mrc mutation (0 available); any Hoxc13 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
abnormal filiform papillae morphology ( J:50569 )
• phenotype is similar to that described for Hoxc13tm1Mrc homozygous mice

craniofacial
abnormal filiform papillae morphology ( J:50569 )
• phenotype is similar to that described for Hoxc13tm1Mrc homozygous mice

integument
abnormal hair growth ( J:50569 )
• phenotype is similar to that described for Hoxc13tm1Mrc homozygous mice
deformed nails ( J:50569 )
• phenotype is similar to that described for Hoxc13tm1Mrc homozygous mice

growth/size/body
abnormal filiform papillae morphology ( J:50569 )
• phenotype is similar to that described for Hoxc13tm1Mrc homozygous mice




Genotype
MGI:3832428
ht2
Allelic
Composition		 Hoxc13tm3Mrc/Hoxc13+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxc13tm3Mrc mutation (0 available); any Hoxc13 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
focal hair loss ( J:50569 )
• at some stages of the hair cycle, lower portions of the face, especially below and behind the eyes, show patchy fur
sparse hair ( J:50569 )
• the ventral coat is sparse, especially in females
• dorsal coat appears relatively normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory