Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxb7tm1Mrc mutation
(0 available);
any
Hoxb7 mutation
(14 available)
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skeleton
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• six rather than seven elements in the sternum of 12% of homozygotes, those with rib abnormalities
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• first rib pair reduced to small knobs in one out of 26 homozygotes
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• 2 out of 26 homozygotes had the first and second ribs fused
• attachment to sternum was typical for first ribs
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa7tm1Mrc mutation
(0 available);
any
Hoxa7 mutation
(17 available)
Hoxb7tm1Mrc mutation
(0 available);
any
Hoxb7 mutation
(14 available)
|
|
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skeleton
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• one out of 11 had the first and second ribs fused
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa7tm1Mrc mutation
(0 available);
any
Hoxa7 mutation
(17 available)
Hoxb7tm1Mrc mutation
(0 available);
any
Hoxb7 mutation
(14 available)
|
|
|
skeleton
|
• 45% had first and second ribs fused
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa7tm1Mrc mutation
(0 available);
any
Hoxa7 mutation
(17 available)
Hoxb7tm1Mrc mutation
(0 available);
any
Hoxb7 mutation
(14 available)
|
|
|
skeleton
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• 71% had first and second ribs fused
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immune system
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• reduced size and altered shape but otherwise normal
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hematopoietic system
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• reduced size and altered shape but otherwise normal
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endocrine/exocrine glands
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• reduced size and altered shape but otherwise normal
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