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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hoxa4tm1Mrc
targeted mutation 1, Mario R Capecchi
MGI:2150391
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hoxa4tm1Mrc/Hoxa4tm1Mrc involves: 129S7/SvEvBrd * C57BL/6J MGI:3612177


Genotype
MGI:3612177
hm1
Allelic
Composition		 Hoxa4tm1Mrc/Hoxa4tm1Mrc
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa4tm1Mrc mutation (0 available); any Hoxa4 mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal pectoral girdle bone morphology ( J:19219 )
• hunched appearance associated with the pectoral girdle sometimes
abnormal cervical vertebrae morphology ( J:19219 )
• dorsal process on C3 as well as C2
• C3 morphology normal otherwise

nervous system
nervous system phenotype ( J:19219 )
N
• normal enteric nervous system

behavior/neurological
hunched posture ( J:19219 )
• hunched appearance associated with the pectoral girdle sometimes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory