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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Scaptm1Mbjg
targeted mutation 1, Joseph L Goldstein
MGI:2148743
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Scaptm1Mbjg/Scaptm1Mbjg
Tg(Mx1-cre)29-4Her/0 		involves: 129S6/SvEvTac * C57BL/6J * SJL MGI:3801617


Genotype
MGI:3801617
cn1
Allelic
Composition		 Scaptm1Mbjg/Scaptm1Mbjg
Tg(Mx1-cre)29-4Her/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scaptm1Mbjg mutation (1 available); any Scap mutation (61 available)
Tg(Mx1-cre)29-4Her mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal lipid homeostasis ( J:69592 )
• following induction with pIpC, fatty acid synthesis is decreased 84% in the liver
decreased circulating free fatty acids level ( J:69592 )
• following induction with pIpC
abnormal cholesterol homeostasis ( J:69592 )
• following induction with pIpC, cholesterol synthesis is decreased 71% in the liver
decreased liver cholesterol level ( J:69592 )
• following induction with pIpC
decreased liver triglyceride level ( J:69592 )
• following induction with pIpC

liver/biliary system
decreased liver cholesterol level ( J:69592 )
• following induction with pIpC
decreased liver triglyceride level ( J:69592 )
• following induction with pIpC




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory