All Phenotypes Mapt<tm1Noh> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mapt^tm1Noh
targeted mutation 1, Nobutaka Hirokawa
MGI:2138030

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mapt^tm1Noh/Mapt^tm1Noh	involves: 129S4/SvJae	MGI:2174969

Allelic Composition	Mapt^tm1Noh/Mapt^tm1Noh
Genetic Background	involves: 129S4/SvJae

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapt^tm1Noh mutation (0 available); any Mapt mutation (453 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal axon morphology ( J:19030 )

• abnormal cerebellar parallel fiber axons; reduction in microtubule (MT) number and density and reduction in frequency of cross-bridges between MTs

• mice exhibit no other obvious abnormalities

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	Alzheimer's disease	DOID:10652		J:19030

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24