Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab23opb2 mutation
(0 available);
any
Rab23 mutation
(33 available)
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mortality/aging
limbs/digits/tail
nervous system
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• ventralized caudal spinal cord
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab23opb2 mutation
(0 available);
any
Rab23 mutation
(33 available)
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mortality/aging
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• most mice die between E12.5 and E14.5
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nervous system
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• at E10.5, mice exhibit a failure to close the posterior neural tube
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vision/eye
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• at E10.5, mice are missing one or both eyes or display eye abnormalities
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limbs/digits/tail
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• mice that survive at E13.5 have extra digits on all four limbs
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embryo
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• at E10.5, mice exhibit a failure to close the posterior neural tube
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk20tm1.1Jegg mutation
(0 available);
any
Cdk20 mutation
(10 available)
Rab23opb2 mutation
(0 available);
any
Rab23 mutation
(33 available)
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embryo
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• P3 interneuron progenitors flanking the floor plate are reduced in number
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• at E10.5
• similar to mice homozygous null for Cdk20 alone
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nervous system
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• P3 interneuron progenitors flanking the floor plate are reduced in number
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• at E10.5
• similar to mice homozygous null for Cdk20 alone
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