Phenotypes associated with this allele

• Allele Symbol: Tp(Y)1Ct^Sxr-a
• Allele Name: Sex reversed, original transposition
• Allele ID: MGI:2136323
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Tp(Y)1Ct^Sxr-a/+	involves: CBA * PCT	MGI:4453571
ot2	X/Tp(Y)1Ct^Sxr-a	involves: CBA * PCT	MGI:4456168

Genotype
MGI:4453571

ht1

• Allelic Composition: Tp(Y)1Ct^Sxr-a/+
• Genetic Background: involves: CBA * PCT

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

small testis ( J:5252 )

• due to loss of germ cell population

reproductive system

abnormal gametogenesis ( J:5252 )

decreased primordial germ cell number ( J:5252 )

• male-type germ cells are present during late fetal and early postnatal development but progressively are lost

absent germ cells ( J:5252 )

• by 10 days of age no germ cells are present

arrest of male meiosis ( J:5252 )

• due to the presence of two X chromosomes

abnormal primary sex determination ( J:5252 )

• chromosomally XX mice inheriting this X-linked genotype develop testes

small testis ( J:5252 )

• due to loss of germ cell population

primary sex reversal ( J:5252 )

• chromosomally XX mice inheriting this X-linked genotype develop testes

cellular

decreased primordial germ cell number ( J:5252 )

• male-type germ cells are present during late fetal and early postnatal development but progressively are lost

absent germ cells ( J:5252 )

• by 10 days of age no germ cells are present

arrest of male meiosis ( J:5252 )

• due to the presence of two X chromosomes

Genotype
MGI:4456168

ot2

• Allelic Composition: X/Tp(Y)1Ct^Sxr-a
• Genetic Background: involves: CBA * PCT

reproductive system

reproductive system phenotype ( J:5252 )

♂N • male development and fertility are normal