Phenotypes associated with this allele

• Allele Symbol: Fgfr3^tm1Wei
• Allele Name: targeted mutation 1, Weizmann Institute of Science
• Allele ID: MGI:2135635
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fgfr3^tm1Wei/Fgfr3^tm1Wei	involves: 129S1/Sv * 129X1/SvJ * MF1	MGI:3639743

Genotype
MGI:3639743

hm1

• Allelic Composition: Fgfr3^tm1Wei/Fgfr3^tm1Wei
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Phenotypic and histological analysis of the Fgfr3^tm1Wei/Fgfr3^tm1Wei mouse

limbs/digits/tail

bowed femur ( J:54829 )

long femur ( J:54829 )

long tail ( J:54829 )

kinked tail ( J:54829 )

skeleton

abnormal long bone morphology ( J:54829 )

• overgrowth of long bones

bowed femur ( J:54829 )

long femur ( J:54829 )

increased long bone epiphyseal plate size ( J:54829 )

• display a greatly expanded growth plate

kyphosis ( J:54829 )

• dorsal kyphosis