All Phenotypes Ell<tm1Hhi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ell^tm1Hhi
targeted mutation 1, Hisamaru Hirai
MGI:1933265

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ell^tm1Hhi/Ell^tm1Hhi	involves: 129X1/SvJ * C57BL/6	MGI:3618623

Allelic Composition	Ell^tm1Hhi/Ell^tm1Hhi
Genetic Background	involves: 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ell^tm1Hhi mutation (0 available); any Ell mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:66498 )

• homozygotes die before E6.5 but after implantation, as evident by the presence of maternal decidual tissues

• at E6.5, ~25% of offspring generated by heterozygous matings (i.e. presumed homozygotes) are already degenerative, exhibiting necrosis and hemorrhage, and undergo gradual resorption by E8.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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