All Phenotypes Tg(ITGB1)0870Fmw MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(ITGB1)0870Fmw
transgene insertion 0870, Fiona M Watt
MGI:1926493

Summary

7 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(ITGA2)1070Fmw/0 Tg(ITGB1)0870Fmw/0	involves: C57BL/10 * CBA	MGI:3583543
cx2	Tg(ITGA2)1075Fmw/0 Tg(ITGB1)0870Fmw/0	involves: C57BL/10 * CBA	MGI:3583546
cx3	Tg(ITGA2)1067Fmw/0 Tg(ITGB1)0870Fmw/0	involves: C57BL/10 * CBA	MGI:3583540
cx4	Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0870Fmw/0	involves: C57BL/10 * CBA	MGI:3583556
cx5	Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0870Fmw/0	involves: C57BL/10 * CBA	MGI:3583559
cx6	Tg(ITGA5)0794Fmw/0 Tg(ITGB1)0870Fmw/0	involves: C57BL/10 * CBA	MGI:3583552
tg7	Tg(ITGB1)0870Fmw/0	involves: C57BL/10 * CBA	MGI:3583562

Allelic Composition	Tg(ITGA2)1070Fmw/0 Tg(ITGB1)0870Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

corneal scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA2)1075Fmw/0 Tg(ITGB1)0870Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

corneal scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA2)1067Fmw/0 Tg(ITGB1)0870Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

corneal scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA5)0844Fmw/0 Tg(ITGB1)0870Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

corneal scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA5)0858Fmw/0 Tg(ITGB1)0870Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

corneal scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGA5)0794Fmw/0 Tg(ITGB1)0870Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

corneal scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

Allelic Composition	Tg(ITGB1)0870Fmw/0
Genetic Background	involves: C57BL/10 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

corneal scarring ( J:30249 )

• adult

eyelids open at birth ( J:30249 )

increased opacity of vitreous body ( J:30249 )

• adult

immune system

eye inflammation ( J:30249 )

• exudate in cornea and eyelid, neonate

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

endocrine/exocrine glands

enlarged sebaceous gland ( J:30249 )

integument

enlarged sebaceous gland ( J:30249 )

dermatitis ( J:30249 )

• age of onset 6 weeks, episodic

abnormal coat/ hair morphology ( J:30249 )

waved hair ( J:30249 )

abnormal hair follicle orientation ( J:30249 )

enlarged hair follicles ( J:30249 )

curly vibrissae ( J:30249 )

short vibrissae ( J:30249 )

abnormal skin morphology ( J:30249 )

hyperkeratosis ( J:30249 )

flaky skin ( J:30249 )

• age of onset 6 weeks, episodic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:30249

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