All Phenotypes Lepr<Tg(Mth11)1Aig> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lepr^{Tg(Mth11)1Aig}
transgene insertion 1, Bernhard Aigner
MGI:1888983

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lepr^{Tg(Mth11)1Aig}/Lepr^{Tg(Mth11)1Aig}	involves: Him:OF1	MGI:2175101

Allelic Composition	Lepr^{Tg(Mth11)1Aig}/Lepr^{Tg(Mth11)1Aig}
Genetic Background	involves: Him:OF1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lepr^{Tg(Mth11)1Aig} mutation (0 available); any Lepr mutation (123 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

polydipsia ( J:61119 )

• polydipsia

growth/size/body

obese ( J:61119 )

• obese

enlarged liver ( J:61119 )

• hepatomegaly due to fat storage

homeostasis/metabolism

hyperglycemia ( J:61119 )

increased circulating insulin level ( J:61119 )

increased urine glucose level ( J:61119 )

• glucosuria

liver/biliary system

enlarged liver ( J:61119 )

• hepatomegaly due to fat storage

renal/urinary system

increased urine glucose level ( J:61119 )

• glucosuria

polyuria ( J:61119 )

• polyuria

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
type 2 diabetes mellitus		DOID:9352	OMIM:125853 OMIM:601283 OMIM:601407 OMIM:603694 OMIM:608036	J:61119

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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