Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mar1tm1Wtg mutation
(1 available);
any
Mar1 mutation
(1 available)
|
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immune system
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• somatic hypermutations are increased on the Mar1tm1Wtg allele
|
hematopoietic system
|
• somatic hypermutations are increased on the Mar1tm1Wtg allele
|
Allelic Composition |
Mar1tm1Wtg/Mar1+
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Genetic Background |
involves: 129S6/SvEvTac * C57BL/6 |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mar1tm1Wtg mutation
(1 available);
any
Mar1 mutation
(1 available)
|
|
|
immune system
|
• in pro-B cells Ikappa VDJ rearrangement is enhanced
|
|
• somatic hypermutations are increased on the Mar1tm1Wtg allele
|
hematopoietic system
|
• somatic hypermutations are increased on the Mar1tm1Wtg allele
|